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Name: tirzepatide mechanism of action for weight loss diabetes: on track to SURPASS current therapy Pharmacogenomics of Tirzepatide: Genomic Insights
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It says discontinuation is recommended before conception or once pregnancy is confirmed

Nadauld LD, Garcia S, Natsoulis G, Bell JM, Miotke L, Hopmans ES, Xu H, Pai RK, Palm C, Regan JF, Chen H, Flaherty P, Ootani A, Zhang NR, Ford JM, Kuo CJ, Ji HP

This may be due to liver or kidney disease, or certain cancers and blood disorders: The aetiological profile of high serum cobalamin predominantly encompasses severe disease entities for which early diagnosis is critical for prognosis